In order to appraise the large dose micron particle size toner pellet by way of the bronchial tube contamination to the mouse lungs' toxic influence, this article from the pathology inspection and experimental animal's BALF (lung syringe fluid), lung aspects and so on refining's biochemistry target as well as pathology slice carries on the discussion. By the 0.5g/kg dosage nanometer particle size toner pellet to the mouse after the bronchial tube injection contamination, previous day injected, altogether injects four times. After 9 days, 4 week, 8 week, 12 weeks takes the lung syringe fluid executes separately and dissects obtains each internal organs, observes the lung syringe fluid and the lung refining biochemistry target change, the lungs tissue slice pathology change. The experiment indicated that toner pellet to mouse's lungs truly virose. From the total protein, the albumin, ACP (acidic phosphatase), LDH (lactic dehydrogenase), NOS (nitrogen monoxide synzyme), MDA (third dial) and so on biochemistry target's elevations as well as the pathology slice looks like, the toner pellet may cause the mouse lungs to have the inflammation symptom, thus influence mouse lungs' normal physiological function.
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In order to assess the high-dose-micron particle size toner particles through the bronchial lungs of mice exposed to toxic effect, this article from the pathological examination and laboratory animals, BALF (lung lavage fluid), lung homogenate, and pathology of the biochemical indicators section to explore the areas. To 0.5g/kg dose of nano-particle size toner particles in mice infected by the bronchial injection, injected the next day, a total of four injections. 9 days, respectively, 4 weeks, 8 weeks, 12 weeks after lung lavage fluid was killed and various organs dissected to observe the lung lavage fluid and lung homogenate biochemical changes in lung tissue of the pathological changes . Experiments show that the toner particles in the lungs of mice is indeed toxic. From the total protein, albumin, ACP (acid phosphatase), LDH (lactate dehydrogenase), NOS (nitric oxide synthase), MDA (malondialdehyde) and other biochemical markers, as well as the increased pathology slice, the toner particles can cause lung inflammation in mice symptoms, thus affecting the normal mouse lung physiology.