Italy is located in Southern Europe and comprises the long, boot-shaped Italian Peninsula, the land between the peninsula and the Alps, and a number of islands including Sicily and Sardinia. Its total area is 301 230 km², of which 294 020 km² is land and 7 210 km² is water. Including islands, Italy has a coastline of 7 600 km on the Adriatic, Ionian, Tyrrhenian (740 km), France (488 km), Austria (430 km), Slovenia (232 km)and Switzerland. San Marino (39 km) and the Vatican City (3.2 km), both entirely surrounded by Italy, account for the remainder. The Apennine Mountains form the peninsula's backbone; the Alps form its northern boundary. The largest of its northern lakes is Garda (143 sq mi; 370 km²); in the centre is Campotosto Lake. The Po, Italy's principal river, flows from the Alps on the western border and crosses the great Padan plain to the Adriatic Sea. Several islands form part of Italy; the largest are Sicily (9,926 sq mi; 25,708 km²) and Sardinia (9,301 sq mi; 24,090 km²). There are several active volcanoes in Italy: Etna, the largest active volcano in Europe; Vulcano; Stromboli; and Vesuvius, the only active volcano on the mainland of Europe.