求大虾翻译！！！谢谢

2025-03-26 23:27:36

推荐回答（3个）

回答1：

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回答2：

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回答3：

结构
GLUD1域结构
每域Glu-BD同--色彩,(P),-BD枢纽,antena螺旋别构监管机构表现球面模型特殊结构GLUD1联合使用两种x射线结构约束--种GTP(1HWZ)第二绑定腺(1NQT)虽真实,该结构向观众展现构相位置,定要GLUD1相应结图谱NADPHGLUD1hexamer单体单元:
1N-terminal
Glu-BD(结合域),其部β-strands
2NAD-BD--强迫要+或NADP间+
3.48-residue
antenna-like投影延伸每NAD-BD线由提升螺旋递减,包含随机线圈条α-helix
c端底向困
NAD-BD坐Glu-BD顶端NAD-BDGlu-BD形催化裂NAD-BD移约束力,基质显著降作两组部、旋转沿轴螺旋NAD-BD面,称轴螺旋,扭顺针向旋转线尚比较启关闭构象变化GLUD1揭示螺旋降线线,看反冲催化裂打越打[1]关关闭十失真,螺旋推入,十相邻线R496建螺旋(见突变)
核结构hexamer堆叠trimers二聚体Glu-BDs单体主要负责建立核单体相位置,其绕轴螺旋每单体受限制三基线trimers披,接受构象变化催化裂打关闭线作intersubunit通讯管道负面协同规定别构许同源GLUD1排列,表明能形线形原物:指前嘌呤监督管理网站表明选择性微带漏波线优点,物发展新本身功能构通增加GLUD1[2]规定
GLUD1形纤维端端hexamers协polimerization催化性关,能着非重要作用comolexes随著杂粕溢酶形等
GLUD1两介质:结合位点NAD-BD,能够醚+或NADP间直接参与+催化程第二调节功能,躺直接轴螺旋,强迫自数据处理,+、或NADH,代表NADPH[3]

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