What's wrong with you(没有the)
What's the matter with you(必须加the)
What's the trouble with you/What's your trouble(要加修饰成分,如the,指示代词等)
What happend to you(这句话说法比较口语,如果用完成时态是What has happened to you,也可以说What is happend to you)
what's up to you/What's up(这句话除了问你怎么了以外还有一种意思就是“最近怎样",是旧友打招呼用的哦)
what is it with you(这句话的it有多种指代,所以他的语气有的时候像是责问:”你TMD到底怎么回事“不过也有其他的语气哦)
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What seems to be the matter是完全可以的,可以把matter换成trouble,意思也是”出了什么事“,”你怎么了“的意思
1.What is the matter with you?
2.What happened to you?
3.what is it with you?
4.what's wrong with you ?
5.what's the matter ?
6.What seems to be the matter?
希望对你有帮助
What is wrong with you?
What is trouble with you?
What is up to you?
What is matter?
What happened to you?
What is with you?