可以使用VBA操作。
关闭其他所有excel,打开一个excel;
复制如下代码到模块中;
运行,选择文件夹。
该代码删除的是A列,可选择其他列。更该代码即可。
Sub Del_Col()
Application.DisplayAlerts = False
Dim myFile As String
Dim myDoc As String
With Application.FileDialog(msoFileDialogFolderPicker)
.Show
.AllowMultiSelect = False
.Title = "选择文件夹"
myFile = .SelectedItems(1)
End With
myDoc = Dir(myFile & "\" & "*.xls*")
Do While Len(myDoc) <> 0
Workbooks.Open (myFile & "\" & myDoc)
Worksheets(1).Columns("A:A").Select '删除A列
Selection.Delete Shift:=xlToLeft
Workbooks(2).Close
Save = True
myDoc = Dir
Loop
Application.DisplayAlerts = True
End Sub